Dementia is a chronic mental disorder wherein individuals suffer from memory disorders, impaired reasoning, and personality changes. Generally, the disorder appears in patients who underwent a brain disease or injury.
Recent research has proved that Infrared light therapy could be a potential answer to people's problems with Dementia. The team discovered several positive attributes to the therapy, including better motor function, memory, and understanding skills of the healthy individual having an average intellectual function as per their age. The study could be a massive contribution to Dementia Treatment Market. It demonstrated that PBM-T (Transcranial Photobiomodulation Therapy) involves infrared light being delivered autonomously to the brain through a specially made helmet worn by the patient.
Through experiments, researchers realized there was a considerable improvement in healthy people who got PBM-T compared to those in the control placebo group. The positive performance was noted in finger tapping (motor function), mathematical processing (memory performance), brain processing speed, and delayed memory. Furthermore, the participants also acknowledged that they experienced no adverse effects due to the treatment.
The team was able to showcase real improvements within memory and several other neurological processes of healthy people as their brains were exposed to a particular infrared light's wavelength for short period intervals. The findings are deemed to be promising indications that infrared light therapy could be immensely beneficial for a patient who has Dementia.
The novel PBM-T helmet devised delivers infrared light from the 14 fan-cooled LED light arrays inside the brain focused on the skull. This is done at a wavelength of approx. 1,060 to 1,080 nanometers wherein 1,368J energy is delivered to the cranium in between every six-minute treatment cycle. This leads to stimulating the mitochondria responsible for generating most chemical energy used by the biochemical reactions of power cells. The process results in the increase of an organic compound, known as ATP (Adenosine Triphosphate), which is present in a minimal amount within dementia patients. Once it rises, it is possible to drive processes within living cells and support nerve cells for repair.
Researchers also believe that the therapy can help increase nitric oxide levels and thus the brain's blood flow. This can be done by simply enhancing the flexibility of the membrane present inside the blood vessels. This causes blood vessels to open up so that more oxygen can get to the white matter within the brain.
The team is aware that much more effort is needed to the advancement of the therapy. However, findings from the initial experiments are highly promising. Their technique could very well become the disease-modifying strategy for Dementia while also having the possibility to alleviate other diseases.
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