Probiotics May Prove Beneficial for Autistic Children

• Analysis
• 05-November-2020

Probiotics have become a popular and favorite ingredient in the natural products industry. Everything from kombuchas and yogurts to breakfast bars and desserts can be an institute with either naturally occurring or added-in probiotics to support gut health and overall well-being.

According to the recent study findings, probiotics may have yet another unforeseen use. The study, known as “Effects of Probiotic Supplementation on Gastrointestinal, Sensory, and Core Symptoms in Autism Spectrum Disorders, came out with fascinated results. The researchers have observed in children without GI [gastrointestinal] symptoms were treated with probiotics significant alteration of core ASD symptoms measured by the ADOS-CSS scores unconnected to the specific intermediation of the effect of various probiotics on GI symptoms.

The authors conducted a double-blind unpredictable, placebo-controlled trial of 85 preschoolers with Autism Spectrum Disorder (ASD), and their average age was 4.2 years. Participants were arbitrarily assigned to placebo or probiotics for six months. The probiotic supplement used was the De Simone Formulation (DSF), a patented mixture approved for children. Each packet comprises 450 billion colony-forming units (CFU) of eight probiotic strains: Bifidobacterium longum, Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium infantis, Lactobacillus acidophilus, Lactobacillus Plantarum, Lactobacillus para-casei, and Lactobacillus delbrueckii subsp. bulgaricus.

The authors noted that there are no differences found between groups who were detected on the primary outcome measure, the Total Autism Diagnostic Observation Schedule - Calibrated Severity Score (ADOS-CSS).” The secondary analysis of the results highlighted two critical findings. When the participants were broken into two groups with or without GI symptoms, the probiotics' effects were more prominent. The group with no GI symptoms treated with probiotics experienced significant refuse in ADOS scores in comparison to that in the placebo group, with an average decrease of 1.14 in Social-Affect and 0.81 in Total ADOS CSS in six months. On the other hand, the group with GI symptoms treated with probiotics found more extensive improvements in GI symptoms, sensory profiles, and adaptive functioning than in the GI group treated with placebo.

The authors also noticed that these research results propose potentially positive effects of probiotics on core autism symptoms in a group of ASD children free from the particular intermediation of the probiotic cause on GI symptoms.
According to the researchers, these results should lead the way for additional studies on larger populations with the hope of finally improving the exactness of medicine in ASD.

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