Culture medium or growth medium is referred to a gel or liquid that is intended to support the growth of microorgamisms, small plants or cells. Generally, Cell Culture Media consists of appropriate sources of compounds and energy that helps in regulation of the cell cycle. When it comes to culture of human cells, they are used to expand the number of cells available and also to differentiate the cells into distinct somatic cell types so that they could help with transplantation.
Typical synthetic cell culture media including DMEM/F-12, DMEM, MEM and RPMI 1640, all contain vitamins, glucose, salts and amino acids in such concentrations that represent the metabolic profile of human plasma. Thus, it would be immensely beneficial for studying cancer or any other disease. This is because results that are more physiologically relevant would enable the researchers to better their understanding of illness and human functions thereafter.
Researchers have unveiled a novel human plasma-like cell culture medium that bears a close resemblance to the natural cellular environment present in the human body. This new development is huge for the Cell Culture Media Market as it would help scientists view and understand the realistic view of cell growth.
The team revealed that the Gibco HPLM (Human Plasma-like Medium) consists of similar salt concentrations as present in human plasma. Further, it also shares the same concentrations as that of over 60 metabolites, such as sugars, amino acids, small organic acids and nucleic acids.
This development of physiologic media might empower scientists to better understand and interpret distinct pharmacological and biological studies. The current study had the objective of creating such physiologic medium that was constructed to look more closely to the metabolic composition of human blood. Thus, the goal was to contribute towards the study of cultured cells in biochemical conditions with greater relevance being put on physiology.
This development in not only great for the cell culture market but also the world in general as HPLM would primarily have applications in immunology research and cancer. The team revealed that HPLM has great potential and might even bring great innovation across diverse areas of scientific research.
It has also been stated that this discovery should be considered as a broad utility in researching cellular metabolism and might be the reason that new metabolic drug interaction or tumour-specific liabilities influenced from environmental metabolic composition are discovered.
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