Invasive Surgical Biopsies undergone in cancer is a difficult, costly and painful affair. As an alternative, detection and analysis of cancer DNA from a patient’s blood itself is coming out to be a promising and attractive technique. This is truer when tumors appear in locations that are difficult to access. Blood Biopsies also referred to as Liquid Biopsies, might be able to overcome much of these issues. This is because they can empower doctors with the ability to track the progress of disease and subsequent treatment in real-time. Further, it can also help researchers how tumors prevent treatment from doing their work with far better resolution.
A research team established that, around 90% of tumor genetic could be identified through blood samples in a recent study on Liquid Biopsy. This can be done through whole-exome sequencing and is applicable for 49% of the patients suffering from advanced cancer. Once the technique is effectively applied and becomes cheaper, the number of patients who can benefit from it will only increase. This is a huge breakthrough for the Liquid Biopsy Market as this form of approach is less invasive and can provide an easy window into cancer’s genome, and has a wide range of applications.
The team's main objective is to be able to use blood biopsies to exhaustively search and identify even the smallest remnants of tumors. Furthermore, as tumors evolve with the advance in the disease and develop, resistance becoming more metastatic, researchers might get access to timepoints through this technology. This would help them decide which therapies would be the best and most effective for the patient.
Blood Biopsies might be an essential key to develop the understanding of metastatic breast cancer, tumor evolution, and drug resistance. They can also play a part in getting a snapshot of the metastatic setting in patients who might not have tissue from a metastatic biopsy. Considering all the results and experiments undertaken by the team, it is evident that Blood Biopsy has reached a high level.
Now, researchers are looking at means through which they can perform large-scale blood biopsies. This would facilitate them with easy access to the cancer genome. Further, it might also bring exciting implications for physicians' methods to monitor treatment response, watch of recurrence, etc. If the scientist can construct the ability to frequently and non-invasively monitor cancer and its treatment, it would lead to revolutionary effects in the cancer treatments sector. Thus, it could potentially increase the accessibility to quality precision medicine approaches.
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